Positive Feedback Loop of Long Noncoding RNA OASL-IT1 and Innate Immune Response Restricts the Replication of Zika Virus in Epithelial A549 Cells

• Main Authors: Yi Wang (Author), Zhiting Huo (Author), Quanshi Lin (Author), Yuxia Lin (Author), Cancan Chen (Author), Yanxia Huang (Author), Changbai Huang (Author), Junsong Zhang (Author), Junfang He (Author), Chao Liu (Author), Ping Zhang (Author)
• Format: Book
• Published: Karger Publishers, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Expression of host noncoding RNAs and coding mRNAs is significantly altered by viral infection. In the current study, we screened the transcriptional profile of human lung epithelial A549 cells infected with Zika virus (ZIKV) by microarray assay. Seventy-nine long noncoding RNAs (lncRNAs) and 140 mR...