Co-ordinated gene expression in the liver and spleen during Schistosoma japonicum infection regulates cell migration.

• Main Authors: Melissa L Burke (Author), Donald P McManus (Author), Grant A Ramm (Author), Mary Duke (Author), Yuesheng Li (Author), Malcolm K Jones (Author), Geoffrey N Gobert (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Determining the molecular events induced in the spleen during schistosome infection is an essential step in better understanding the immunopathogenesis of schistosomiasis and the mechanisms by which schistosomes modulate the host immune response. The present study defines the transcriptional and cel...