PBPK modeling to predict drug‐drug interactions of ivosidenib as a perpetrator in cancer patients and qualification of the Simcyp platform for CYP3A4 induction

Abstract Ivosidenib is a potent, targeted, orally active, small‐molecule inhibitor of mutant isocitrate dehydrogenase 1 (IDH1) that has been approved in the United States for the treatment of adults with newly diagnosed acute myeloid leukemia (AML) who are greater than or equal to 75 years of age or...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Jayaprakasam Bolleddula (Auteur), Alice Ke (Auteur), Hua Yang (Auteur), Chandra Prakash (Auteur)
Formaat: Boek
Gepubliceerd in: Wiley, 2021-06-01T00:00:00Z.
Onderwerpen:
Online toegang:Connect to this object online.
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Internet

Connect to this object online.

3rd Floor Main Library

Exemplaargegevens van 3rd Floor Main Library
Plaatsingsnummer: A1234.567
Kopie 1 Beschikbaar