Gastrodin Alleviates Angiotensin II-Induced Hypertension and Myocardial Apoptosis via Inhibition of the PRDX2/p53 Pathway In Vivo and In Vitro

• Main Authors: Nanhui Xu (Author), Qiurong Xie (Author), Youqin Chen (Author), Jiapeng Li (Author), Xiuli Zhang (Author), Huifang Zheng (Author), Ying Cheng (Author), Meizhu Wu (Author), Aling Shen (Author), Lihui Wei (Author), Mengying Yao (Author), Yanyan Yang (Author), Thomas J. Sferra (Author), Anjum Jafri (Author), Yi Fang (Author), Jun Peng (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gastrodin, a highly potent compound found in the traditional Chinese medicine <i>Gastrodia elata</i> Blume, exhibits significant antihypertensive properties. However, its role and the mechanism behind its protective effects on hypertensive cardiac conditions are not well understood. This...