Hedgehog signaling in gastrointestinal carcinogenesis and the gastrointestinal tumor microenvironment

• Main Authors: Jinghui Zhang (Author), Jiajun Fan (Author), Xian Zeng (Author), Mingming Nie (Author), Jingyun Luan (Author), Yichen Wang (Author), Dianwen Ju (Author), Kai Yin (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The Hedgehog (HH) signaling pathway plays important roles in gastrointestinal carcinogenesis and the gastrointestinal tumor microenvironment (TME). Aberrant HH signaling activation may accelerate the growth of gastrointestinal tumors and lead to tumor immune tolerance and drug resistance. The intera...