Spatial metabolomics highlights metabolic reprogramming in acute myeloid leukemia mice through creatine pathway

• Main Authors: Yucheng Bao (Author), Jing Qiao (Author), Wenjie Gong (Author), Ruihong Zhang (Author), Yanting Zhou (Author), Yinyin Xie (Author), Yuan Xie (Author), Jiuming He (Author), Tong Yin (Author)
• Format: Book
• Published: Elsevier, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute myeloid leukemia (AML) is recognized as an aggressive cancer that is characterized by significant metabolic reprogramming. Here, we applied spatial metabolomics to achieve high-throughput, in situ identification of metabolites within the liver metastases of AML mice. Alterations at metabolite...