Spatial metabolomics highlights metabolic reprogramming in acute myeloid leukemia mice through creatine pathway

• मुख्य लेखकों: Yucheng Bao (लेखक), Jing Qiao (लेखक), Wenjie Gong (लेखक), Ruihong Zhang (लेखक), Yanting Zhou (लेखक), Yinyin Xie (लेखक), Yuan Xie (लेखक), Jiuming He (लेखक), Tong Yin (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2024-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Acute myeloid leukemia (AML) is recognized as an aggressive cancer that is characterized by significant metabolic reprogramming. Here, we applied spatial metabolomics to achieve high-throughput, in situ identification of metabolites within the liver metastases of AML mice. Alterations at metabolite...