Coumarin carbonic anhydrase inhibitors from natural sources
Coumarins constitute a relatively new class of inhibitors of the zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1), possessing a unique inhibition mechanism, acting as "prodrug inhibitors." They undergo the hydrolysis of the lactone ring mediated by the esterase activity of CA. The formed 2-...
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Taylor & Francis Group,
2020-01-01T00:00:00Z.
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