Population pharmacokinetic modeling of paired plasma-breast milk lamivudine data for estimation of infant exposure in breastfeeding mother-infant pairs

• Hauptverfasser: Francis Williams Ojara (Verfasst von), Aida N. Kawuma (Verfasst von), Shadia Nakalema (Verfasst von), Isabella Kyohairwe (Verfasst von), Ritah Nakijoba (Verfasst von), Mohammed Lamorde (Verfasst von), Henry Pertinez (Verfasst von), Saye Khoo (Verfasst von), Catriona Waitt (Verfasst von)
• Format: Buch
• Veröffentlicht: Wiley, 2024-11-01T00:00:00Z.
• Schlagworte: article
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Abstract Around 1.2 million women living with HIV give birth annually, majority of whom will breastfeed their infants while receiving antiretroviral therapy (ART). Lamivudine, a component of first‐line ART regimens crosses from maternal plasma to breast milk, with measurable concentrations in some b...