Population pharmacokinetic modeling of paired plasma-breast milk lamivudine data for estimation of infant exposure in breastfeeding mother-infant pairs

• Egile Nagusiak: Francis Williams Ojara (Egilea), Aida N. Kawuma (Egilea), Shadia Nakalema (Egilea), Isabella Kyohairwe (Egilea), Ritah Nakijoba (Egilea), Mohammed Lamorde (Egilea), Henry Pertinez (Egilea), Saye Khoo (Egilea), Catriona Waitt (Egilea)
• Formatua: Liburua
• Argitaratua: Wiley, 2024-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Around 1.2 million women living with HIV give birth annually, majority of whom will breastfeed their infants while receiving antiretroviral therapy (ART). Lamivudine, a component of first‐line ART regimens crosses from maternal plasma to breast milk, with measurable concentrations in some b...