Population pharmacokinetic modeling of paired plasma-breast milk lamivudine data for estimation of infant exposure in breastfeeding mother-infant pairs

• Päätekijät: Francis Williams Ojara (Tekijä), Aida N. Kawuma (Tekijä), Shadia Nakalema (Tekijä), Isabella Kyohairwe (Tekijä), Ritah Nakijoba (Tekijä), Mohammed Lamorde (Tekijä), Henry Pertinez (Tekijä), Saye Khoo (Tekijä), Catriona Waitt (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Wiley, 2024-11-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Around 1.2 million women living with HIV give birth annually, majority of whom will breastfeed their infants while receiving antiretroviral therapy (ART). Lamivudine, a component of first‐line ART regimens crosses from maternal plasma to breast milk, with measurable concentrations in some b...