Population pharmacokinetic modeling of paired plasma-breast milk lamivudine data for estimation of infant exposure in breastfeeding mother-infant pairs

• Autori principali: Francis Williams Ojara (Autore), Aida N. Kawuma (Autore), Shadia Nakalema (Autore), Isabella Kyohairwe (Autore), Ritah Nakijoba (Autore), Mohammed Lamorde (Autore), Henry Pertinez (Autore), Saye Khoo (Autore), Catriona Waitt (Autore)
• Natura: Libro
• Pubblicazione: Wiley, 2024-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Around 1.2 million women living with HIV give birth annually, majority of whom will breastfeed their infants while receiving antiretroviral therapy (ART). Lamivudine, a component of first‐line ART regimens crosses from maternal plasma to breast milk, with measurable concentrations in some b...