Population pharmacokinetic modeling of paired plasma-breast milk lamivudine data for estimation of infant exposure in breastfeeding mother-infant pairs

• Автори: Francis Williams Ojara (Автор), Aida N. Kawuma (Автор), Shadia Nakalema (Автор), Isabella Kyohairwe (Автор), Ritah Nakijoba (Автор), Mohammed Lamorde (Автор), Henry Pertinez (Автор), Saye Khoo (Автор), Catriona Waitt (Автор)
• Формат: Книга
• Опубліковано: Wiley, 2024-11-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract Around 1.2 million women living with HIV give birth annually, majority of whom will breastfeed their infants while receiving antiretroviral therapy (ART). Lamivudine, a component of first‐line ART regimens crosses from maternal plasma to breast milk, with measurable concentrations in some b...