Tunable and sustained-release characteristics of venlafaxine hydrochloride from chitosan-carbomer matrix tablets based on in situ formed polyelectrolyte complex film coating

• Autores principales: Xiaofei Zhang (Autor), Xiangqin Gu (Autor), Xiaodan Wang (Autor), Huimin Wang (Autor), Shirui Mao (Autor)
• Formato: Libro
• Publicado: Elsevier, 2018-11-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The objective of this study is to design sustained-release tablets using matrix technology, which can well control the release of highly water-soluble drugs with good system robustness and simple preparation process. Taking venlafaxine hydrochloride (VH) as a drug model, the feasibility of using chi...