Identification of an irreversible PPARγ antagonist with potent anticancer activity

• Main Authors: Youyi Peng (Author), Qiang Zhang (Author), Robert M. Zielinski (Author), Richard D. Howells (Author), William J. Welsh (Author)
• Format: Book
• Published: Wiley, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Melanoma is responsible for most skin cancer deaths, and its incidence continues to rise year after year. Different treatment options have been developed for melanoma depending on the stage of the disease. Despite recent advances in immuno‐ and targeted therapies, advanced melanoma remains...