Effects of small interfering RNAs targeting fascin on human esophageal squamous cell carcinoma cell lines

• Main Authors: Garcia Jose (Author), Martorell Miguel (Author), Sato Fumiaki (Author), Tsunoda Shigeru (Author), Iwai Akira (Author), Nagayama Satoshi (Author), Hashimoto Yosuke (Author), Ito Tetsuo (Author), Ortiz Cristian M (Author), Perez Ana (Author), Shimada Yutaka (Author)
• Format: Book
• Published: BMC, 2010-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Fascin induces membrane protrusions and cell motility. Fascin overexpression was associated with poor prognosis, and its downregulation reduces cell motility and invasiveness in esophageal squamous cell carcinoma (ESCC). Using a stab...