Emerging Preclinical Applications of Humanized Mouse Models in the Discovery and Validation of Novel Immunotherapeutics and Their Mechanisms of Action for Improved Cancer Treatment

• Egile Nagusiak: Isha Karnik (Egilea), Zhisheng Her (Egilea), Shu Hui Neo (Egilea), Wai Nam Liu (Egilea), Qingfeng Chen (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2023-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Cancer therapeutics have undergone immense research over the past decade. While chemotherapies remain the mainstay treatments for many cancers, the advent of new molecular techniques has opened doors for more targeted modalities towards cancer cells. Although immune checkpoint inhibitors (ICIs) have...