DOPE/CHEMS-Based EGFR-Targeted Immunoliposomes for Docetaxel Delivery: Formulation Development, Physicochemical Characterization and Biological Evaluation on Prostate Cancer Cells

• Main Authors: Thais da Silva Moreira (Author), Alan Denis Olivindo Silva (Author), Bianca Rodrigues Farias Vasconcelos (Author), Elias da Silva Santos (Author), Ana Carolina Cruz de Sousa (Author), João Vito Barroso de Freitas (Author), Yara Santiago de Oliveira (Author), Laura Maria Teodorio Vidal (Author), Fábio de Oliveira Silva Ribeiro (Author), Alyne Rodrigues de Araújo (Author), José de Brito Vieira Neto (Author), Cláudia do Ó Pessoa (Author), Raquel Petrilli (Author), Josimar O. Eloy (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Docetaxel (DTX) is a non-selective antineoplastic agent with low solubility and a series of side effects. The technology of pH-sensitive and anti-epidermal growth factor receptor (anti-EGFR) immunoliposomes aims to increase the selective delivery of the drug in the acidic tumor environment to cells...