A C-Terminal Fragment of Chlorotoxin Retains Bioactivity and Inhibits Cell Migration

• Main Authors: Mohadeseh Dastpeyman (Author), Paul Giacomin (Author), David Wilson (Author), Matthew J. Nolan (Author), Paramjit S. Bansal (Author), Norelle L. Daly (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chlorotoxin was originally isolated from the venom of the Israeli scorpion Leiurus quinquestriatus, and has potential as a tumor imaging agent based on its selective binding to tumor cells. Several targets have been suggested for chlorotoxin including voltage-gated chloride channels, and it has been...