Ex vivo isolated human vessel perfusion system for the design and assessment of nanomedicines targeted to the endothelium

• Main Authors: Taras Lysyy (Author), Laura G. Bracaglia (Author), Lingfeng Qin (Author), Claire Albert (Author), Jordan S. Pober (Author), George Tellides (Author), W. Mark Saltzman (Author), Gregory T. Tietjen (Author)
• Format: Book
• Published: Wiley, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Endothelial cells play a central role in the process of inflammation. Their biologic relevance, as well as their accessibility to IV injected therapeutics, make them a strong candidate for treatment with molecularly‐targeted nanomedicines. Typically, the properties of targeted nanomedicines...