Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis

• Main Authors: Marina Badenes (Author), Abdulbasit Amin (Author), Ismael González-García (Author), Inês Félix (Author), Emma Burbridge (Author), Miguel Cavadas (Author), Francisco José Ortega (Author), Érika de Carvalho (Author), Pedro Faísca (Author), Stefania Carobbio (Author), Elsa Seixas (Author), Dora Pedroso (Author), Ana Neves-Costa (Author), Luís F. Moita (Author), José Manuel Fernández-Real (Author), António Vidal-Puig (Author), Ana Domingos (Author), Miguel López (Author), Colin Adrain (Author)
• Format: Book
• Published: Elsevier, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Obesity is the result of positive energy balance. It can be caused by excessive energy consumption but also by decreased energy dissipation, which occurs under several conditions including when the development or activation of brown adipose tissue (BAT) is impaired. Here we evaluated whet...