Three-dimensional hepatocyte culture system for the study of Echinococcus multilocularis larval development.

• Main Authors: Li Li (Author), Bing Chen (Author), Hongbin Yan (Author), Yannan Zhao (Author), Zhongzi Lou (Author), Jianqiu Li (Author), Baoquan Fu (Author), Xingquan Zhu (Author), Donald P McManus (Author), Jianwu Dai (Author), Wanzhong Jia (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatocyte-based metacestode culture is an attractive method to study alveolar echinococcosis (AE), but it is limited by the relatively short lifespan of cultured hepatocytes in maintaining their normal function.We describe a three-dimensional (3D) hepatic culture system developed from co-cultured h...