Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder

Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder

Background and Purpose:Mitragyna speciosa extract and kratom alkaloids decrease alcohol consumption in mice at least in part through actions at the δ-opioid receptor (δOR). However, the most potent opioidergic kratom alkaloid, 7-hydroxymitragynine, exhibits rewarding properties and hyperlocomotion p...

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Main Authors: Anna M. Gutridge (Author), Soumen Chakraborty (Author), Balazs R. Varga (Author), Elizabeth S. Rhoda (Author), Alexander R. French (Author), Arryn T. Blaine (Author), Quinten H. Royer (Author), Haoyue Cui (Author), Jinling Yuan (Author), Robert J. Cassell (Author), Márk Szabó (Author), Susruta Majumdar (Author), Richard M. van Rijn (Author)
Format: Book
Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
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