Mechanism of crocin I on ANIT-induced intrahepatic cholestasis by combined metabolomics and transcriptomics

• Main Authors: Dandan Song (Author), Pei Zhu (Author), Yankai Dong (Author), Mengchao Wang (Author), Anna Zhao (Author), Hongdong Xia (Author), Yunting Chen (Author), Qingguang Zhou (Author), Lun Xiang (Author), Junyi Zhang (Author), Guangming Luo (Author), Yangjing Luo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Intrahepatic cholestasis (IC) is a disorder of bile production, secretion, and excretion with various causes. Crocin I (CR) is effective in the treatment of IC, but its underlying mechanisms need to be further explored. We aimed to reveal the therapeutic mechanism of crocin I for IC by c...