In silico and antithrombotic studies of 1,3,4-oxadiazoles derived from benzimidazole

In the present study, a series of 1,3,4-oxadiazole derivatives (4a-4k) derived from benzimidazole were docked onto factor Xa (PDB: 1NFY) protein using SYBYLX 2.1. and also evaluated for in vitro clot lysis for thrombolytic activity. The synthesized molecules were also screened for in silico ADME stu...

Full description

Saved in:
Bibliographic Details
Main Authors: B. Vishwanathan (Author), B. M. Gurupadayya (Author), K. Venkata Sairam (Author)
Format: Book
Published: Bangladesh Pharmacological Society, 2015-12-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available