Suppressing dengue-2 infection by chemical inhibition of Aedes aegypti host factors.

• Main Authors: Seokyoung Kang (Author), Alicia R Shields (Author), Natapong Jupatanakul (Author), George Dimopoulos (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue virus host factors (DENV HFs) that are essential for the completion of the infection cycle in the mosquito vector and vertebrate host represent potent targets for transmission blocking. Here we investigated whether known mammalian DENV HF inhibitors could influence virus infection in the arth...