Fluorine-thiol displacement probes for acetaminophen's hepatotoxicity

Fluorine-thiol displacement probes for acetaminophen's hepatotoxicity

Chemicals possessing reactive electrophiles can denature innate proteins leading to undesired toxicity, and the overdose-induced liver injury by drugs containing electrophiles has been one of the major causes of non-approval and withdraw by the US Food and Drug Administration (FDA). Elucidating the...

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Main Authors: Benjamin L. Prather (Author), Shuyue Ji (Author), Yue Zhao (Author), Femil Joseph Shajan (Author), Mi Zhao (Author), Zakey Yusuf Buuh (Author), Robert Maloney (Author), Rui Zhang (Author), Carson Cohen (Author), Rongsheng E. Wang (Author)
Format: Book
Published: Elsevier, 2023-01-01T00:00:00Z.
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