Genetic association between the APOE ε4 allele, toxicant exposures and Gulf war illness diagnosis

• Main Authors: L Abdullah (Author), A Nkiliza (Author), D Niedospial (Author), G Aldrich (Author), G Bartenfelder (Author), A Keegan (Author), M Hoffmann (Author), M Mullan (Author), N Klimas (Author), J Baraniuk (Author), F Crawford (Author), M Krengel (Author), L Chao (Author), K Sullivan (Author)
• Format: Book
• Published: BMC, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Introduction Exposure to nerve agents, pyridostigmine bromide (PB), pesticides, and oil-well fires during the 1991 Gulf War (GW) are major contributors to the etiology of Gulf War Illness (GWI). Since the apolipoprotein E (APOE) ε4 allele is associated with the risk of cognitive decline wit...