Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium(II)-Catalyzed <i>ortho</i>-C(sp²)-H-Hydroxylation

• 主要な著者: Alexander Berger (著者), Talea Knak (著者), Anna-Lene (著者), Korana Mudrovcic (著者), Vinayak Singh (著者), Mathew Njoroge (著者), Bjoern B. Burckhardt (著者), Mohanraj Gopalswamy (著者), Beate Lungerich (著者), Lutz Ackermann (著者), Holger Gohlke (著者), Kelly Chibale (著者), Rainer Kalscheuer (著者), Thomas Kurz (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2022-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The continuous, worldwide spread of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) endanger the World Health Organization's (WHO) goal to end the global TB pandemic by the year 2035. During the past 50 years, very few new drugs have been approved by medical age...