Anxiolytic-like effects of hochuekkito in lipopolysaccharide-treated mice involve interleukin-6 inhibition

• Main Authors: Soichiro Ushio (Author), Yudai Wada (Author), Mizuki Nakamura (Author), Daiki Matsumoto (Author), Kota Hoshika (Author), Shoya Shiromizu (Author), Naohiro Iwata (Author), Satoru Esumi (Author), Makoto Kajizono (Author), Yoshihisa Kitamura (Author), Toshiaki Sendo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hochuekkito (HET) is a Kampo medicine used to treat postoperative and post-illness general malaise and decreased motivation. HET is known to regulate immunity and modulate inflammation. However, the precise mechanism and effects of HET on inflammation-induced central nervous system disorders remain...