Cytotoxicity of catechol towards human glioblastoma cells via superoxide and reactive quinones generation Citotoxicidade do catecol para células de glioblastoma humano via geração de superóxido e quinonas reativas

• Main Authors: Marco Roberto Guimarães Pereira (Author), Elineusa Silva de Oliveira (Author), Flávio Augusto Guerreiro Aragão de Villar (Author), Maria Socorro Grangeiro (Author), Júlia Fonseca (Author), Ana Rita Silva (Author), Maria de Fátima Dias Costa (Author), Sílvia Lima Costa (Author), Ramon dos Santos El-Bachá (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2004-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

It is known that the exposure to benzene in the petroleum industry causes lympho-haematopoietic cancer among workers. However, there is little data concerning the toxicity of benzene to the central nervous system. Benzene easily penetrates the brain where it is metabolized to catechol. Since catecho...