The anticancer potential of chemical constituents of Moringa oleifera targeting CDK-2 inhibition in estrogen receptor positive breast cancer using in-silico and in vitro approches

• Главные авторы: Rida Sultan (Автор), Abrar Ahmed (Автор), Li Wei (Автор), Hamid Saeed (Автор), Muhammad Islam (Автор), Muhammad Ishaq (Автор)
• Формат: ‌
• Опубликовано: BMC, 2023-11-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Abstract Most of the breast cancers are estrogen receptor-positive recurring with a steady rate of up to 20 years dysregulating the normal cell cycle. Dinaciclib is still in clinical trials and considered as a research drug against such cancers targeting CDK2. The major goal of this study was to ide...