Novel APC gene mutations associated with protein alteration in diffuse type gastric cancer

• Main Authors: Souvik Ghatak (Author), Payel Chakraborty (Author), Sandeep Roy Sarkar (Author), Biswajit Chowdhury (Author), Arup Bhaumik (Author), Nachimuthu Senthil Kumar (Author)
• Format: Book
• Published: BMC, 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The role of adenomatous polyposis coli (APC) gene in mitosis might be critical for regulation of genomic stability and chromosome segregation. APC gene mutations have been associated to have a role in colon cancer and since gastric and colon tumors share some common genetic lesio...