An association study of ABCG2 rs2231142 on the concentrations of allopurinol and its metabolites

• Main Authors: Marc‐Olivier Pilon (Author), Grégoire Leclair (Author), Essaïd Oussaïd (Author), Isabelle St‐Jean (Author), Martin Jutras (Author), Marie‐Josée Gaulin (Author), Ian Mongrain (Author), David Busseuil (Author), Jean Lucien Rouleau (Author), Jean‐Claude Tardif (Author), Marie‐Pierre Dubé (Author), Simon deDenus (Author)
• Format: Book
• Published: Wiley, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract ABCG2 is a gene that codes for the human breast cancer resistance protein (BCRP). It is established that rs2231142 G>T, a single nucleotide polymorphism of the ABCG2 gene, is associated with gout and poor response to allopurinol, a uric acid‐lowering agent used to treat this condition. I...