Membrane-disruptive peptides/peptidomimetics-based therapeutics: Promising systems to combat bacteria and cancer in the drug-resistant era

• Main Authors: Liming Lin (Author), Jiaying Chi (Author), Yilang Yan (Author), Rui Luo (Author), Xiaoqian Feng (Author), Yuwei Zheng (Author), Dongyi Xian (Author), Xin Li (Author), Guilan Quan (Author), Daojun Liu (Author), Chuanbin Wu (Author), Chao Lu (Author), Xin Pan (Author)
• Format: Book
• Published: Elsevier, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Membrane-disruptive peptides/peptidomimetics (MDPs) are antimicrobials or anticarcinogens that present a general killing mechanism through the physical disruption of cell membranes, in contrast to conventional chemotherapeutic drugs, which act on precise targets such as DNA or specific enzymes. Owin...