Effect of Clemastine on Neurophysiological Outcomes in an Ovine Model of Neonatal Hypoxic-Ischemic Encephalopathy

• Main Authors: Jana Krystofova Mike (Author), Yasmine White (Author), Rachel S. Hutchings (Author), Christian Vento (Author), Janica Ha (Author), Ariana Iranmahboub (Author), Hadiya Manzoor (Author), Anya Gunewardena (Author), Cheryl Cheah (Author), Aijun Wang (Author), Brian D. Goudy (Author), Satyan Lakshminrusimha (Author), Janel Long-Boyle (Author), Jeffrey R. Fineman (Author), Donna M. Ferriero (Author), Emin Maltepe (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Originally approved by the U.S. Food and Drug Administration (FDA) for its antihistamine properties, clemastine can also promote white matter integrity and has shown promise in the treatment of demyelinating diseases such as multiple sclerosis. Here, we conducted an in-depth analysis of the feasibil...