Synthesis and evaluation of 2,4,5-trisubstitutedthiazoles as carbonic anhydrase-III inhibitors

• Main Authors: Bilal A. Al-Jaidi (Author), Pran Kishore Deb (Author), Soha Taher Telfah (Author), Abdel Naser Dakkah (Author), Yazan A. Bataineh (Author), Qutaiba Ahmed Al Khames Aga (Author), Mohammad A. Al-dhoun (Author), Ala' Ali Ahmad Al-Subeihi (Author), Haifa'a Marouf Odetallah (Author), Sanaa K. Bardaweel (Author), Raghuprasad Mailavaram (Author), Katharigatta N. Venugopala (Author), Anroop B. Nair (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of 17 compounds (12-16 b) with 2,4,5-trisubstitutedthiazole scaffold having 5-aryl group, 4-carboxylic acid/ester moiety, and 2-amino/amido/ureido functional groups were synthesised, characterised, and evaluated for their carbonic anhydrase (CA)-III inhibitory activities using the size excl...