Pharmacokinetics of dipeptide mimetic BDNF GSB-106 in rats

• المؤلفون الرئيسيون: V. P. Zherdev (مؤلف), G. B. Kolyvanov (مؤلف), A. A. Litvin (مؤلف), P. O. Bochkov (مؤلف), O. G. Gribakina (مؤلف), R. V. Shevchenko (مؤلف), A. V. Tarasyuk (مؤلف), T. A. Gudasheva (مؤلف)
• التنسيق: كتاب
• منشور في: LLC "Publisher OKI", 2019-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Pharmacokinetics of the GSB-106 in variety of administration ways in rats was studied. After single oral administration the test substance was determined for 4 h in the blood plasma. Half-life was 0.65 h. The GSB-106 tissue availability in high-vascularized organs (liver, kidney, spleen) was over th...