Pharmacokinetics of dipeptide mimetic BDNF GSB-106 in rats

• Main Authors: V. P. Zherdev (Author), G. B. Kolyvanov (Author), A. A. Litvin (Author), P. O. Bochkov (Author), O. G. Gribakina (Author), R. V. Shevchenko (Author), A. V. Tarasyuk (Author), T. A. Gudasheva (Author)
• Formato: Livro
• Publicado em: LLC "Publisher OKI", 2019-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Pharmacokinetics of the GSB-106 in variety of administration ways in rats was studied. After single oral administration the test substance was determined for 4 h in the blood plasma. Half-life was 0.65 h. The GSB-106 tissue availability in high-vascularized organs (liver, kidney, spleen) was over th...