Cryptolepine Suppresses Colorectal Cancer Cell Proliferation, Stemness, and Metastatic Processes by Inhibiting WNT/β-Catenin Signaling

• Hlavní autoři: Jude Tetteh Quarshie (Autor), Kwadwo Fosu (Autor), Nicholas Awuku Offei (Autor), Augustine Kojo Sobo (Autor), Osbourne Quaye (Autor), Anastasia Rosebud Aikins (Autor)
• Médium: Kniha
• Vydáno: MDPI AG, 2023-07-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Colorectal cancer (CRC) is the third most frequent cancer and the second leading cause of cancer-related deaths globally. Evidence shows that over 90% of CRC cases are initiated by a deregulated Wingless Integrated Type-1 (WNT)/β-catenin signaling pathway. The WNT/β-catenin pathway also promotes CRC...