Modeling Parkinson's Disease Using Induced Pluripotent Stem Cells

• Main Authors: Xinchao Hu (Author), Chengyuan Mao (Author), Liyuan Fan (Author), Haiyang Luo (Author), Zhengwei Hu (Author), Shuo Zhang (Author), Zhihua Yang (Author), Huimin Zheng (Author), Huifang Sun (Author), Yu Fan (Author), Jing Yang (Author), Changhe Shi (Author), Yuming Xu (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parkinson's disease (PD) is the second most common neurodegenerative disease. The molecular mechanisms of PD at the cellular level involve oxidative stress, mitochondrial dysfunction, autophagy, axonal transport, and neuroinflammation. Induced pluripotent stem cells (iPSCs) with patient-specifi...