Synthesis, Characterization, and Anticancer Activity of Benzothiazole Aniline Derivatives and Their Platinum (II) Complexes as New Chemotherapy Agents

• Main Authors: Md. Kamrul Islam (Author), Ah-Rum Baek (Author), Bokyung Sung (Author), Byeong-Woo Yang (Author), Garam Choi (Author), Hyun-Jin Park (Author), Yeoun-Hee Kim (Author), Minsup Kim (Author), Seongmin Ha (Author), Gang-Ho Lee (Author), Hee-Kyung Kim (Author), Yongmin Chang (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We describe the synthesis, characterization, molecular modeling, and in vitro anticancer activity of three benzothiazole aniline (BTA) ligands and their corresponding platinum (II) complexes. We designed the compounds based on the selective antitumor properties of BTA, along with three types of meta...