Targeting acetyl-CoA carboxylase 1 for cancer therapy
Metabolic adaptation is an emerging hallmark of tumors. De novo fatty acid synthesis is an important metabolic process to produce metabolic intermediates for energy storage, biosynthesis of membrane lipids and generation of signaling molecules. Acetyl-CoA carboxylase 1 (ACC1) is a critical enzyme in...
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Frontiers Media S.A.,
2023-02-01T00:00:00Z.
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