Targeting acetyl-CoA carboxylase 1 for cancer therapy

• 主要な著者: Yong Yu (著者), Qingzhu Nie (著者), Ziyi Wang (著者), Yu Di (著者), Xiaolong Chen (著者), Kaiming Ren (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Metabolic adaptation is an emerging hallmark of tumors. De novo fatty acid synthesis is an important metabolic process to produce metabolic intermediates for energy storage, biosynthesis of membrane lipids and generation of signaling molecules. Acetyl-CoA carboxylase 1 (ACC1) is a critical enzyme in...