Fabrication of pH/Reduction Sensitive Polyethylene Glycol-Based Micelles for Enhanced Intracellular Drug Release

• Главные авторы: Yang Yang (Автор), Fuwei Yang (Автор), Xiaotian Shan (Автор), Jiamin Xu (Автор), Wenjie Fang (Автор), Juan Zhou (Автор), Lipeng Qiu (Автор), Jinghua Chen (Автор)
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• Опубликовано: MDPI AG, 2021-09-01T00:00:00Z.
• Предметы: article
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At present, the drug is still difficult to release completely and quickly only with single stimulation. In order to promote the rapid release of polymeric micelles at tumor site, pH/reduction sensitive polymers (PCT) containing disulfide bonds and orthoester groups were synthesized. The PCT polymers...