REV-ERB is essential in cardiac fibroblasts homeostasis

• मुख्य लेखकों: Xiaokang Luo (लेखक), Shiyang Song (लेखक), Lei Qi (लेखक), Chih-Liang Tien (लेखक), Hui Li (लेखक), Weiyi Xu (लेखक), Theodore Lemuel Mathuram (लेखक), Thomas Burris (लेखक), Yuanbiao Zhao (लेखक), Zheng Sun (लेखक), Lilei Zhang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

REV-ERB agonists have shown antifibrotic effects in the heart and other organs. The function of REV-ERB in the cardiac fibroblasts remains unstudied. Here, we characterize the functional difference of REV-ERB in mouse embryonic fibroblasts and cardiac fibroblasts using genetic deletion of REV-ERBα a...