Rigid Macrocycle Metal Complexes as CXCR4 Chemokine Receptor Antagonists: Influence of Ring Size

• Main Authors: Isaline Renard (Author), Thomas D'huys (Author), Benjamin P. Burke (Author), Trisha Ajoleza (Author), Amy N. Cain (Author), Neil L. Funwie (Author), Abid Khan (Author), Danny L. Maples (Author), Randall D. Maples (Author), Dallas L. Matz (Author), Graeme McRobbie (Author), Robert Ullom (Author), Timothy J. Prior (Author), Douglas P. Linder (Author), Tom Van Loy (Author), Timothy J. Hubin (Author), Dominique Schols (Author), Stephen J. Archibald (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Understanding the role of chemokine receptors in health and disease has been of increasing interest in recent years. Chemokine receptor CXCR4 has been extensively studied because of its defined role in immune cell trafficking, HIV infection, inflammatory diseases, and cancer progression. We have dev...