Enhancement of the In Vitro Antitumor Effects of Berberine Chloride When Encapsulated within Small Extracellular Vesicles

• Váldodahkkit: Abir Salek (Dahkki), Mouna Selmi (Dahkki), Mahassen Barboura (Dahkki), M. Carmen Martinez (Dahkki), Leila Chekir-Ghedira (Dahkki), Ramaroson Andriantsitohaina (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2022-09-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Berberine hydrochloride (BRB) is an isoquinoline alkaloid with promising anticancer efficacies. However, application of BRB had been hampered by its poor aqueous solubility, low gastrointestinal absorption, and rapid metabolism. The present study takes advantage of small extracellular vesicles (sEVs...