2‐Deoxy‐d‐glucose induces deglycosylation of proinflammatory cytokine receptors and strongly reduces immunological responses in mouse models of inflammation

• Main Authors: Ikuno Uehara (Author), Mitsuko Kajita (Author), Atsuko Tanimura (Author), Shigeaki Hida (Author), Munehiko Onda (Author), Zenya Naito (Author), Shinsuke Taki (Author), Nobuyuki Tanaka (Author)
• Format: Book
• Published: Wiley, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Anti‐proinflammatory cytokine therapies against interleukin (IL)‐6, tumor necrosis factor (TNF)‐α, and IL‐1 are major advancements in treating inflammatory diseases, especially rheumatoid arthritis. Such therapies are mainly performed by injection of antibodies against cytokines or cytokine...