Evaluating the performance of machine‐learning regression models for pharmacokinetic drug-drug interactions

• Prif Awduron: Jaidip Gill (Awdur), Marie Moullet (Awdur), Anton Martinsson (Awdur), Filip Miljković (Awdur), Beth Williamson (Awdur), Rosalinda H. Arends (Awdur), Venkatesh Pilla Reddy (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Wiley, 2023-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Abstract Combination therapy or concomitant drug administration can be associated with pharmacokinetic drug-drug interactions, increasing the risk of adverse drug events and reduced drug efficacy. Thus far, machine‐learning models have been developed that can classify drug-drug interactions. However...