Inhibitory effect of AK-7 mediates by apoptosis, increases DNA fragmentation and caspase-3 activity in human glioblastoma multiforme cells

Sirtuins (SIRTs) which are nicotinamide adenine dinucleotide (NAD+) dependent class III histondeacetylases have a controversial role in cancer. In this study, the effect of pharmacological inhibition of AK-7, a SIRT2 inhibitor, was investigated in U87 glioblastoma multiforme cells. The cytotoxic eff...

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Main Authors: Ebru Güçlü (Author), İlknur Çınar Ayan (Author), Hasibe Vural (Author)
Format: Book
Published: Bangladesh Pharmacological Society, 2022-06-01T00:00:00Z.
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3rd Floor Main Library

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