The NRF2-mediated oxidative stress response pathway is associated with tumor cell resistance to arsenic trioxide across the NCI-60 panel

• Hauptverfasser: Liu Qian (Verfasst von), Zhang Hao (Verfasst von), Smeester Lisa (Verfasst von), Zou Fei (Verfasst von), Kesic Matt (Verfasst von), Jaspers Ilona (Verfasst von), Pi Jingbo (Verfasst von), Fry Rebecca C (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2010-08-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Drinking water contaminated with inorganic arsenic is associated with increased risk for different types of cancer. Paradoxically, arsenic trioxide can also be used to induce remission in patients with acute promyelocytic leukemia (A...