The NRF2-mediated oxidative stress response pathway is associated with tumor cell resistance to arsenic trioxide across the NCI-60 panel

• Main Authors: Liu Qian (Author), Zhang Hao (Author), Smeester Lisa (Author), Zou Fei (Author), Kesic Matt (Author), Jaspers Ilona (Author), Pi Jingbo (Author), Fry Rebecca C (Author)
• Format: Book
• Published: BMC, 2010-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Drinking water contaminated with inorganic arsenic is associated with increased risk for different types of cancer. Paradoxically, arsenic trioxide can also be used to induce remission in patients with acute promyelocytic leukemia (A...