GH dysfunction in Engrailed-2 knockout mice, a model for autism spectrum disorders
Insulin-like growth factor 1 (IGF-1) signaling promotes brain development and plasticity. Altered IGF-1 expression has been associated to autism spectrum disorders (ASD). IGF-1 levels were found increased in the blood and decreased in the cerebrospinal fluid of ASD children. Accordingly, IGF-1 treat...
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Frontiers Media S.A.,
2014-09-01T00:00:00Z.
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