GH dysfunction in Engrailed-2 knockout mice, a model for autism spectrum disorders

• প্রধান লেখক: Giovanni eProvenzano (লেখক), Elena eClementi (লেখক), Sacha eGenovesi (লেখক), Manuela eScali (লেখক), Prem Prakash Tripathi (লেখক), Paola eSgadò (লেখক), Yuri eBozzi (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2014-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Insulin-like growth factor 1 (IGF-1) signaling promotes brain development and plasticity. Altered IGF-1 expression has been associated to autism spectrum disorders (ASD). IGF-1 levels were found increased in the blood and decreased in the cerebrospinal fluid of ASD children. Accordingly, IGF-1 treat...